That is a sore point with him

That’s a permanent state for her

That's an old donkey.

That makes one’s hair stand on end.

That’s the way the cookie crumbles

That’s beside the point

That’s no comfort to me

That’s a lazy man’s load

That's enough.

That's not my daughter.

That's a stupid comparison!

That’s a different matter

That's a beautiful rainbow.

That interview was sheer torture

That’s a puzzler

Is that enough to live on?

That does not mean anything.

That's funny!

That metallic red Alfa Romeo Spider over there really suits my fancy

That’s quite another matter

That is it in a nutshell

That sounds suspiciously like ’no’ to me

that’s about the gauge of it

That sounds like a Rube Goldberg solution, there must be a simpler way!

That question is beyond/outside my purview